Individual Study / LASA

Longitudinal Aging Study Amsterdam

Longitudinal Aging Study Amsterdam

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LASA is designed to be an interdisciplinary, longitudinal study. Although basically scientific in nature, the study should provide a basis for developing and evaluating (central and local government) policy in the field of aging. The global objective of current policy in the field of aging can be formulated as enhancing the autonomy and quality of life of older persons. It is expected that by using longitudinal data, policy relevant aspects of aging can be identified and new policy aims can be developed. Moreover, assumptions from which policy measures are developed can be tested, and effects of policy changes can be assessed prospectively. LASA is primarily an observational study; the database will allow testing of various specific hypotheses. Full intervention studies will not be included in LASA.

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Investigators Contacts
  • Dr. Marjolein Broese van Groenou
    VU University Amsterdam
  • Dr. Hannie Comijs
    VU University medical centre Amsterdam
  • Dr. Marja Aartsen
    VU University Amsterdam
  • Dr. Natasja van Schoor
    VU University medical centre Amsterdam
  • Dr. Dorly Deeg
    VU University medical centre Amsterdam

Conception

Study design
Cohort
Start Year
1992
Follow Up

Every three years, the participants are re-examined.

Supplementary Information

See http://www.lasa-vu.nl/community/staff/LASAstaff.html for a complete list of LASA staff.

Function of investigators:

  • Dr Dorly Deeg (principal investigator)
  • Dr Marja Aartsen (head of group on social functioning)
  • Dr Marjolein Broese van Groenou ( head of group use of care)
  • Dr Hannie Comijs (head of group on emotional and cognitive functioning)
  • Dr Natasja van Schoor (co-head of group on physical functioning)

Marker Paper

Huisman M, Poppelaars J, van der Horst M, Beekman AT, Brug J, van Tilburg TG, Deeg DJ. Cohort profile: the Longitudinal Aging Study Amsterdam. Int J Epidemiol. 2011 Aug;40(4):868-76.

PUBMED 21216744

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
5,132
Number of participants with biosamples
4,188

Access

Availability of data and biosamples

Data
Biosamples
Other

Timeline

Populations

The LASA cohort is based on a nationally representative sample of older adults aged 55–85 years (years of birth 1908–37), based in three geographic regions in The Netherlands. These three regions were selected so that an optimal representation of the older Dutch population would be achieved, with respondents from the protestant north-east, the catholic south and secular parts of The Netherlands and from both urbanized and rural areas within each of these regions. The sample was recruited from municipal registries in 1992, with an oversampling of older people and older men in particular.

Selection Criteria
Minimum age
55
Maximum age
85
Newborns
Twins
Countries
  • Netherlands
Territory

Amsterdam, Wormerland, Waterland (three municipalities in the West), Zwolle, Ommen, Genemuiden, Zwartsluis, Hasselt (North-East), and Oss, Uden, Boekel (South)

Recruitment

Sources of recruitment
  • Participants from existing studies
Participants from existing studies
  • NESTOR study on Living Arrangements and Social Networks (LSN)

Number of participants

Number of participants
3,107
Number of participants with biosamples
2,840
Data Collection Events
# Name Description Start End
0 LASA Wave B

Face-to-face interview.

1992-09 1993-09
0 LASA Wave C

Main face-to-face interview, medical in-home interview and a telephone interview with a respondend or a proxy.

1995-09 1996-10
0 LASA Wave D

Main face-to-face interview, medical in-home interview and a telephone interview with a respondend or a proxy.

1998-09 1999-10
0 LASA Wave E

Main face-to-face interview, medical in-home interview and a telephone interview with a respondend or a proxy.

2001-09 2002-10
0 LASA Wave F

Main face-to-face interview, medical in-home interview and a telephone interview with a respondend or a proxy.

2005-09 2006-10
0 LASA Wave G

Main face-to-face interview, medical in-home interview and a telephone interview with a respondend or a proxy.

2008-09 2009-10
0 LASA wave H

Main face-to-face interview, medical in-home interview and a telephone interview with the respondent or a proxy.

Total response for this wave = 1522 (First and second cohort)

2011-09 2012-10

Nationally representative sample of older adults aged 55-65 years (Years of birth 1938-1947). Same sampling frame as the first cohort. 

Selection Criteria
Minimum age
55
Maximum age
65
Newborns
Twins
Countries
  • Netherlands
Territory

Amsterdam, Wormerland, Waterland (three municipalities in the West), Zwolle, Ommen, Genemuiden, Zwartsluis, Hasselt (North-East), and Oss, Uden, Boekel (South)

Recruitment

Sources of recruitment
  • General population
General Population
  • Volunteer enrolment

Number of participants

Number of participants
1,002
Number of participants with biosamples
748
Data Collection Events
# Name Description Start End
0 LASA2 Wave A/B

Main face-to-face interview and medical in-home interview.

2002-09 2003-09
0 LASA Wave F

Main face-to-face interview, medical in-home interview and a telephone interview with a respondend or a proxy.

2005-09 2006-10
0 LASA Wave G

Main face-to-face interview, medical in-home interview and a telephone interview with a respondend or a proxy.

2008-09 2009-10
0 LASA wave H

Main face-to-face interview, medical in-home interview and a telephone interview with the respondent or a proxy.

Total response for this wave = 1522 (First and second cohort)

2011-09 2012-10

Nationally representative sample of older adults aged 55-65 years. Same sampling frame as the first cohort. 

Selection Criteria
Minimum age
55
Maximum age
65
Newborns
Twins
Countries
  • Netherlands
Territory

Amsterdam, Wormerland, Waterland (three municipalities in the West), Zwolle, Ommen, Genemuiden, Zwartsluis, Hasselt (North-East), and Oss, Uden, Boekel (South)

Recruitment

Sources of recruitment
  • General population
General Population
  • Volunteer enrolment

Number of participants

Number of participants
1,023
Number of participants with biosamples
600
Data Collection Event

Main face-to-face interview, medical in-home interview

Start Date
2012-10
End Date
2014-06
Data sources
  • Questionnaires
  • Physical measures
  • Biosamples
Data sources - Biosamples
  • Blood